Gelastic epilepsy: Beyond hypothalamic hamartomas
نویسندگان
چکیده
منابع مشابه
Gelastic epilepsy: Beyond hypothalamic hamartomas
Gelastic epilepsy or laughing seizures have been historically related to children with hypothalamic hamartomas. We report three adult patients who had gelastic epilepsy, defined as the presence of seizures with a prominent laugh component, including brain imaging, surface/invasive electroencephalography, positron emission tomography, and medical/surgical outcomes. None of the patients had hamar...
متن کاملGelastic epilepsy and hypothalamic hamartomas: neuroanatomical analysis of brain lesions in 100 patients.
Hypothalamic hamartomas present with isolated fits of ictal laughter (gelastic epilepsy) or a combination of gelastic and other types of seizures. Many of these patients also suffer from cognitive decline, neuropsychiatric comorbidities and precocious puberty. Although there is a large body of anecdotal evidence about hypothalamic hamartomas and gelastic seizures, many questions still remain to...
متن کاملInterstitial radiosurgery in the treatment of gelastic epilepsy due to hypothalamic hamartomas.
The authors evaluated a new stereotactic radiosurgical approach in seven patients with gelastic epilepsy due to hypothalamic hamartomas. Stereotactic implantation of 125I-seeds into the hamartoma was feasible in six patients. At follow-up at least 1 year after interstitial radiotherapy, two patients had become seizure-free within 2 months, and two others had only persisting auras. There were no...
متن کاملHypothalamic hamartomas causing gelastic epilepsy: Two cases and a review of the literature
Two cases of hypothalamic hamartomas causing gelastic epilepsy are described. The clinical presentations and the radiological features are presented, and the mechanisms involved in laughing attacks are discussed. The literature is reviewed and it is suggested the complete extirpation of the hamartomas is the treatment of choice in gelastic epilepsy.
متن کاملEpilepsy syndromes associated with hypothalamic hamartomas
PURPOSE Hypothalamic hamartoma (HH) related epilepsy presents with gelastic seizures (GS), other seizure types and cognitive deterioration. Although seizure origin in GS has been well established, non-GS are poorly characterized. Their relationship with the HH and cognitive deterioration remains poorly understood. We analyzed seizure type, spread pattern in non-GS and their relationship with th...
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ژورنال
عنوان ژورنال: Epilepsy & Behavior Case Reports
سال: 2015
ISSN: 2213-3232
DOI: 10.1016/j.ebcr.2015.07.001